Ponatinib is a really good BCR-ABL inhibitor. It’s used to treat CML and a type of ALL called Ph ALL, especially in people who haven’t been helped by other kinase inhibitors. The drug is made to hit lots of different kinases, making it really good at fighting the disease and less likely to stop working over time.
Ponatinib comes in two strengths: 15 mg and 45 mg, and they come as those easy-to-swallow tablets with a coating. For adults, the usual dose is 45 mg taken once a day, and it doesn’t matter if you eat before you take it. You can buy Ponatinib in bottles with 30 tablets each, so it’s just right for a month’s worth at once.
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