This med called selpercatinib specifically blocks something called RET kinases, which play a big role in certain kinds of cancer like NSCLC and medullary thyroid cancer. It stops RET kinase from doing its thing. The pill comes in sizes—40 mg and 80 mg capsules.
You should take 160 mg of the stuff two times a day, no matter if you’ve eaten or not. You’ll find these pills in bottles, with 60 in each. The main thing in this med hits on these RET kinases, which kind of go nuts in cancer cells with those RET fusions.
This is a type of med called a tyrosine kinase inhibitor, or TKI for short. How it works? It stops those cancer cells from growing by not letting certain signals get turned on. It works best in these cancer types where RET fusions are a normal sign.
It’s made to keep those unwanted side effects to a minimum by just keeping the bad stuff in check and letting regular cell stuff keep happening. They’ve tested this stuff in studies and it’s okay for some RET-fusion-positive cancers.
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