Trametinib is like a roadblock for MEK, a big deal protein in this whole RAS/RAF/MEK/ERK thing that’s all about how cells grow and change. It’s like a one-trick pony, really good at dealing with BRAF V600E/K-mutant melanoma and NSCLC. It stops MEK from sending those growth signals, which in turn keeps cancer cells from getting bigger and spreading.
You can get trametinib in two doses, a half milligram and two milligrams, both in those coated tablets. For adults, the go-to dose is two milligrams, and it’s best to take it on an empty stomach once a day. Don’t break, crush, or chew the pill, okay? It comes in bottles with 30 tablets in each.
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